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Found 614 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Study of Anesthesia Approaches for Coronary Artery Bypass Surgery Sustainability

18 years or above
All genders
Observational
The purpose of this research study is to compare 2 anesthesia approaches used during elective coronary artery bypass graft surgery (a type of heart bypass surgery). The study will compare an “optimized recovery” anesthesia approach with the hospital’s usual anesthesia practice. The researchers will look at recovery in the ICU …
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E-diary vs Paper Diary in Binge Eating Disorder (A-3650-0001)

18 years or below
All genders
Interventional
The purpose of this study is to examine how binge eating episodes are recorded using two different diary formats: a paper diary and an electronic diary and to see whether both formats collect information in the same way and to understand which of the two formats is easier to use
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Comparative Effects of Mulligan Bent Leg Raise Versus Spinal Mobilization With Leg Movement in Lumbar Radiculopathy

20 years - 40 years
All genders
Interventional
Lumbar radiculopathy is a spinal nerve root disorder often caused by lumbar disc herniation or compression, leading to radiating leg pain, restricted movement, and functional difficulties. This condition significantly disrupts daily activities and overall quality of life. While medication and exercise are common treatments, manual therapy techniques are gaining recognition …
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Social Prescriptions and Micro-Learning to Improve Care for Cancer Patients and Their Support Persons (PRISMA)

18 years or above
Accepts healthy volunteer
All genders
Optimal patient-centered care is often not being delivered to cancer patients, especially to vulnerable populations like those living in underserved rural areas. This body of work will develop and pilot test a multicomponent intervention approach designed to improve the care and outcomes of cancer patients and their support persons (SPs) …
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Sensory and Physical Reactions to Beverage Cues (AUD-CUE)

21 years - 70 years
All genders
Interventional
The goal of this clinical trial is to evaluate changes in craving and sensory responses to different beverage cues in adults (aged 21-70) with current mild or greater alcohol use disorder (AUD). The main questions it aims to answer are:Does exposure to different beverage cues elicit distinct changes in subjective …
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Study of Neurofeedback Training for Bothersome Tinnitus Distress

18 years - 70 years
All genders
Interventional
The purpose of this research study is to learn whether neurofeedback training can reduce distress and improve emotional and thinking health in people with bothersome tinnitus. Tinnitus is when you hear sounds like ringing or buzzing that other people cannot hear. This study focuses on tinnitus that is not “pulsatile” …
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Phase 3 Study of Nemvaleukin Alfa in Combination With Pembrolizumab in Patients With Platinum-Resistant Epithelial Ovarian Cancer (ARTISTRY-7)

18 years or above
Female
Phase 3
This is a Phase 3, multicenter, open-label, randomized study of nemvaleukin in combination with pembrolizumab versus protocol-specific Investigator's choice chemotherapy in patients with platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer. Interested in participating? For more information about this research study or other cancer-related clinical trials at IU Simon Comprehensive …
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Targeting Polyamines using DFMO in Persons with Type 1 Diabetes: A Randomized Double-Masked Placebo-Controlled Phase I/II Study to Evaluate the Safety Tolerability and Initial Pharmacodynamics of Multiple Ascending Doses

Cynthia K Teskey
E
Ellie Ryan
12 years - 40 years
All genders
The purpose of this study is to determine if different doses of a drug known as DFMO have an effect on reducing the amount of stress that is experienced by the body's beta cells and preserves residual c-peptide.
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A Multicenter Randomized Double-Blind Parallel-Group Placebo-Controlled Dose-Ranging Phase 2b Study of the Safety and Efficacy of Continuous 48-Hour Intravenous Infusions of BMS-986231 in Hospitalized Patients with Heart Failure and Impaired Systolic Function

18 years - 100 years
All genders
Acute Decompensated Heart Failure (ADHF) is when the signs and symptoms of heart failure get worse. These symptoms can include difficulty breathing (dyspnea), leg or foot swelling, and fatigue. ADHF is a common and potentially serious cause of troubled breathing. It is caused by your heart not pumping as strong …
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OBSERVATIONAL CLINICAL STUDY PROTOCOL An Observational Multicenter Study of the Prevalence of Cerebrotendinous Xanthomatosis (CTX) in Patient Populations Diagnosed with Early-Onset Idiopathic Bilateral Cataracts

100 years or below
All genders
The purpose of this study is to understand better how many people who have been diagnosed with early-onset idiopathic bilateral cataracts may have a rare but treatable disease called Cerebrotendinous Xanthomatosis.
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