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Found 614 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Phase I/II study augmenting TAK-659 action in relapsed/refractory AML by addition of the proteasome inhibitor Ixazomib Big Ten Cancer Research Consortium BTCRC-HEM17-092

18 years - 100 years
All genders
Phase 1/2
The purpose of this study is to test the safety and efficacy of combining two drugs, ixazomib and TAK-659. It will also evaluate the number of patients whose tumor responded after receiving ixazomib and TAK-659.
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School Evaluation and Supports of Children with Pelizaeus-Merzbacher disease

3 years - 25 years
All genders
Describe how schools look at the needs of children with Pelizaeus-Merzbacher disease and how schools support those children in their school environment to help with learning needs
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MRI Determination of Femoral Neck Cortical Porosity in Chronic Kidney Disease Metabolic Bone Disease (CKD-MBD)

21 years - 50 years
Accepts healthy volunteer
All genders
The purpose of this study is to help physicians predict bone fractures in patients with chronic kidney disease (CKD). Patients with kidney failure have an increased risk of hip fractures. Unfortunately, the bone density scans normally used in osteoporosis do not predict these fractures very well. However, new Magnetic Resonance …
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A RANDOMIZED, PHASE II STUDY COMPARING TRASTUZUMAB AND VINORELBINE IN COMBINATION WITH AVELUMAB OR AVELUMAB AND UTOMILUMAB (41BB/CD137 AGONIST), IN PATIENTS WITH HER2-POSITIVE METASTATIC BREAST CANCER WHO HAVE PROGRESSED ON PRIOR TRASTUZUMAB AND PERTUZUMAB:The

18 years - 100 years
All genders
Phase 2
To determine whether the addition of avelumab to the combination of trastuzumab and vinorelbine will improve progression-free survival (PFS) compared to the trastuzumab and vinorelbine combination alone in patients with advanced HER2-positive breast cancer. To determine whether the addition of utomilumab to the combination of avelumab, trastuzumab, and vinorelbine will …
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Repetitive Transcranial Magnetic Stimulation as a Probe of Episodic Memory Neurocircuitry in Schizophrenia

18 years - 40 years
All genders
This study proposes to combine functional magnetic resonance imaging (fMRI) with inhibitory Low Frequency (1 Hz) and excitatory High Frequency (20 Hz) repetitive Transcranial Magnetic Stimulationn (rTMS) in schizophrenia.
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Neural correlates of consumers' mental imagery.

18 years - 55 years
Accepts healthy volunteer
Female
The purpose of this study is to investigate how the brain processes various stimuli in the context of consumer decision-making. This study will identify the neural correlates of consumers' mental imagery.
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Randomized Phase II/III Trial of Radiotherapy with Concurrent MEDI4736 (Durvalumab) vs. Radiotherapy with Concurrent Cetuximab in Patients with Stage III-IVB Head and Neck Cancer with a Contraindication to Cisplatin

18 years - 100 years
All genders
The purpose of this study is to compare any good and bad effects of usual radiation plus the study treatment, MEDI4736 (durvalumab), to the usual therapy of radiation plus cetuximab in patients with head and neck cancer who cannot take the drug cisplatin.
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The effect of foot type on ankle movement during an inversion perturbation

18 years - 26 years
Accepts healthy volunteer
All genders
The proposed study aims to determine if different foot types have an impact on maximum inversion, time to maximum inversion, and inversion velocity during a dynamic perturbation task.
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Insights into the Lid Margin: Characterization of Membrane Associated Mucins in Ocular Surface Disease

18 years - 100 years
Accepts healthy volunteer
All genders
Dry eye disease affects millions of people worldwide and due to an incomplete understanding of the pathogenesis of the disease, it is widely underdiagnosed and undermanaged by clinicians. Understanding the contribution of the proteins involved in maintaining boundary lubrication between the ocular surface and eyelids, specifically mucins, may lead to …
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An ERP Examination of Facial Affect Recognition

18 years - 59 years
Accepts healthy volunteer
All genders
The purpose of this study is to examine the underlying neuronal correlates of facial recognition. We will specifically be examining how different faces correspond with brain activity and how features of personality impact the processing of faces and related brain activity.
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