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Found 614 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Phase I trial of azacitidine plus nivolumab following reduced-intensity allogeneic PBSC transplantation for patients with AML and high-risk myelodysplasia

18 years - 100 years
All genders
The purpose of this study is to find the maximum safe dose of nivolumab alone, and of nivolumab combined with azacitidine after reduced-intensity allogeneic peripheral blood stem cell (PBSC) transplantation. Another purpose is to see how the study drugs affect different aspects of transplant such as infection and disease response.
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A Qualitative Inquiry on Amputation Decisions for Bone Cancer in the Lower Limb

14 years - 100 years
All genders
The purpose of this study is to explore the lived experience and patient education (knowledge transfer) of patients and families when making a surgical decision for the treatment of osteosarcoma.
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Black Educational Encouragement

18 years - 100 years
Accepts healthy volunteer
All genders
You will be asked to participate in an online survey that assess your views and perceptions surrounding your experiences while in school as well as the ways you have attempted to overcome issues that have arose. 
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Reliability of spoken discourse in speakers with aphasia

18 years - 100 years
Accepts healthy volunteer
All genders
This study is recruiting participants to take part in a new study examining speech and attention abilities in older adult speakers and speakers with brain injury (e.g. stroke, traumatic brain injury, etc).
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Clinical Transplant-Related Long-term Outcomes of Alternative Donor Allogeneic Transplantation (CTRLALT-D)

100 years or below
All genders
The primary objective is to estimate and compare overall survival between the two arms:  patients who are Very Likely to find a MUD versus those who are Very Unlikely to find  a MUD.
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A PHASE II TRIAL OF EPIGENETIC PRIMING IN PATIENTS WITH NEWLY DIAGNOSED ACUTE MYELOID LEUKEMIA

22 years or below
All genders
The purpose of this study is to determine if epigenetic priming with DNA methyltransferase inhibitors (DMTi) prior to chemotherapy blocks is safe and effective in treating children with acute myeloid leukemia (AML).
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A Multicenter Phase II Study of Vaccines to Prevent Recurrence in Patients with HER-2 Positive Breast Cancer

18 years - 100 years
All genders
The main purpose of this study is to evaluate the safety of each investigational study vaccine and to evaluate the effect on the time to disease recurrence (assessed by disease free survival).
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A Randomized Phase II/III Study of Conventional Chemotherapy +/- Uproleselan (GMI-1271) in Older Adults with Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy

60 years - 100 years
All genders
The purpose of this study is to see if we lower the chance of AML returning or getting worse by adding a new drug to the usual combination of drugs.
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BMT CTN 1703/1801: A Randomized, Multi-Center, Phase III Trial of Tacrolimus/ Methotrexate versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (PROGRESS III)/Companion Study: Microbiome and Immune Reconstitution in Cellular Therapies and Hematopoietic Stem Cell Transplantation (Mi-Immune)

18 years - 100 years
All genders
The primary objective of the trial is to compare 1 year GVHD-free, relapse-free survival (GRFS) between the two GVHD prophylaxis regimens.
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Intelligibility of speakers with and without aphasia

18 years - 35 years
Accepts healthy volunteer
All genders
People with aphasia can speak very fluently but make little sense or can speak non-fluently making it difficult to understand their intended message. This research will investigate how well listeners are able to understand the speech of people with aphasia compared speakers without aphasia
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