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Found 616 results

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Effects of Modern Chemotherapy Regimens on Spermatogenesis and Steroidogenesis in Adolescent and Young Adult (AYA) Survivors of Osteosarcoma

18 years - 50 years
Male
This research trial studies saliva, semen, and blood samples to determine effects of chemotherapy on fertility in osteosarcoma survivors. Study biospecimen samples from osteosarcoma survivors in the laboratory may help doctors learn whether chemotherapy causes fertility problems and to learn more about the long term effects.

A Phase 1 Study of Pevonedistat (MLN4924) a Cullin Ligase Inhibitor in Combination With Temozolomide and Irinotecan in Pediatric Patients With Recurrent or Refractory Solid Tumors

1 years - 21 years
All genders
This phase I trial studies the side effects and best dose of pevonedistat when giving together with irinotecan hydrochloride and temozolomide in treating patients with solid tumors or lymphoma that have come back after a period of improvement or that do not respond to treatment.

A First-in-Human Phase I Trial to Determine the Safety and the Pharmacokinetic Profile of DSP-0509 a Synthetic Toll-Like Receptor 7 (TLR-7) Agonist in Adult Patients With Advanced Solid Tumors

18 years - 100 years
All genders
This is a Phase 1, open label, multi-center study of intravenously administered DSP-0509 in adult subjects with advance solid tumors that are refractory to standard treatment.

Functional and Neurochemical Substrates of Chemotherapy-Related Cognitive Deficits

18 years - 55 years
Female
The purpose of this study is to understand how chemotherapy alters brain function and brain chemistry.

Biodistribution and dosimetry of the investigational PET agent 68Ga-P16-093 in prostate cancer patients with biochemical recurrence undergoing clinical 68Ga-PSMA-11 PET/CT

18 years - 100 years
Male
Whole body biodistribution and dosimetry with preliminary comparison to PSMA-11 in prostate cancer patients with biochemical recurrence

A Phase II trial of Atezolizumab (anti-PDL1) with Carboplatin in Patients with Metastatic Triple Negative Breast Cancer

18 years - 100 years
All genders
The purpose of this study is to test how well the combination of study drugs, carboplatin and atezolizumab, keeps metastatic triple negative breast cancer from growing compared to taking carboplatin only.

Neural and Cognitive Bases of Language Processing

30 years - 85 years
All genders
Purdue Aphasia Research Lab invites healthy older adults and individuals with stroke-induced aphasia to participate in a NIH-funded research project. The goal of the project is to examine how different types of cues facilitate sentence production and comprehension in persons with aphasia. The findings will lead to development of more …

A Phase 1/2 Trial of VX15/2503 in Children Adolescents or Young Adults With Recurrent or Relapsed Solid Tumors

1 years - 30 years
All genders
This phase I/II trial studies the side effects and best dose of anti-SEMA4D monoclonal antibody VX15/2503 (VX15/2503) and to see how well it works in treating younger patients with solid tumors that have come back after treatment, or do not respond to treatment.
 Dietary Nitrate and Muscle Power with Aging

Dietary Nitrate and Muscle Power with Aging

65 years - 79 years
All genders
The purpose of this study is to see if drinking beetroot juice (BRJ) is beneficial for aging subjects.

How Learning is Influenced by Trait Competitiveness and Self-Efficacy in a Multi-phase Competition

18 years - 100 years
All genders
The purpose of this study is to discover how personality types may affect someone?s ability to learn and improve themselves. Specifically, learn and improve in a competition.
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