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Found 614 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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A Phase 1 Study to Evaluate the Safety and Tolerability of a Study Drug in Subjects with Early Alzheimer's Disease (AD)

55 years - 85 years
All genders
Phase 1
This study will test the safety and tolerability of an experimental study drug that may delay Alzheimer’s disease (AD) onset or slow the progression of possible AD-related damage due to protein build-up in the brain.   Methods include measuring the amount of study drug and drug-related material in the cerebrospinal fluid …
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Dopamine and Smoking Behaviors

18 years - 55 years
All genders
The purpose of this study is to understand how and where brain dopamine reacts while you smoke a cigarette.
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Biomarkers of endothelial dysfunction in pediatric patients receiving high intensity chemotherapy/irradiation

18 years or below
All genders
The purpose of this study is to collect blood specimens and data from patients undergoing stem cell transplant.
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Phase II Randomized Double-Blind Study of mFOLFIRINOX plus Ramucirumab versus mFOLFIRINOX plus placebo in Advanced Pancreatic Cancer Patients HCRN GI14-198

Y
Yu Wang
18 years - 100 years
All genders
The purpose of this study is to find out what effects, good and/or bad, there are to adding the drug ramucirumab (RAM) to the usual chemotherapy regimen.
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A Phase II Trial of Chemotherapy plus Pembrolizumab in patients with advanced NSCLC previously treated with PD-1 or PD-L1 Inhibitor

18 years - 100 years
All genders
This is a single-arm phase II study of continuation immunotherapy with pembrolizumab following initial benefit with a PD-1 or PD-L1 inhibitor.
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A Randomized Phase 3 Study of Vincristine Dactinomycin Cyclophosphamide (VAC) Alternating with Vincristine and Irinotecan (VI) Versus VAC/VI Plus Temsirolimus (TORI Torisel NSC# 683864 IND# 122782) in Patients with Intermediate Risk (IR) Rhabdomyosarcoma (RMS)

40 years or below
All genders
The purpose of this study is to compare the event-free survival of patients with IR RMS treated with surgery, radiotherapy and VAC alternating with VI (VAC/VI) to that of patients treated with surgery, radiotherapy and VAC/VI plus temsirolimus (TORI).
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Observational Disease Registry of Patients Treated with Systemic Mold-Active Triazoles

18 years - 100 years
All genders
This study seeks to describe representative real-world patterns of care for the management of invasive fungal infections (IFIs) ,including invasive mold infection (IMI). Specifically, the study goals are to examine real world patient characteristics and treatment patterns, associated healthcare resource utilization, and outcomes associated with use of mold-active triazoles (MATs) …
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Comparative Effectiveness of Interventions to Improve Screening Among Rural Women

50 years - 74 years
Female
The purpose of this study is to compare the effectiveness of a tailored interactive DVD (TIDVD) vs telephone patient navigation (PN) + tailored interactive DVD (TIDVD) vs Usual Care in increasing screening rates for Breast Cancer (BC), Cervical Cancer (CC), and colorectal cancer (CRC) among women 50 -74 years living …
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Pilot Study of Cabozantinib for Recurrent or Progressive High-Grade Glioma in Children

2 years - 21 years
All genders
The purpose of this study is to find out if the drug, Cabozantinib, is safe and tolerable in pediatric patients with refractory and/or recurrent high grade gliomas (HGG) who have previously received radiation therapy. We are also looking to see if the drug has an effect on the rate at …
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Observational Study for Pediatric Rheumatic Diseases: The CARRA Registry

21 years or below
All genders
The purpose of this study is to collect information regarding treatment plans and disease activity of current patients with pediatric onset rheumatic diseases, in the hopes that this information can help improve treatments and health outcomes for future patients.
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