Immunomodulatory effects of IL-33 in atopic dermatitis

Recruiting
18 years - 100 years
All
Phase N/A
1 Location

Brief description of study

The purpose of this study is to define the effects of neutralizing a certain protein affecting healthy and diseased skin and blood from patients with atopic dermatitis and to determine if the response to neutralization will differ between different subtypes of atopic dermatitis

Detailed description of study

The purpose of this study is to define the effects of neutralizing a certain protein (IL-33) affecting healthy and diseased skin and blood from patients with atopic dermatitis and to determine if the response to neutralization will differ between different subtypes of atopic dermatitis.

Participants will be paid for their participation.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: healthy
  • Age: 18 years - 100 years
  • Gender: All

Inclusion Criteria
Active moderate to severe atopic dermatitis (AD) or healthy individuals who are similarly matched to enrolled AD patients in age, race, and sex
Exclusion Criteria
Systemic immunosuppressant in the past 6 months
Use of UVB or UVA phototherapies or tanning beds in the past 3 months
Use of topical steroids in/around biopsy sites >1 (preferably 2) week(s)
History of primary or secondary immunodeficiency disorders/diseases
History of keloid scar formation
History of allergy to lidocaine or other amide local anesthetics
History of bleeding disorders that could result in prolonged bleeding
History of prolonged or poor wound healing

Updated on 04 Aug 2024. Study ID: 1508749599

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