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Found 206 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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AVATAR anesthesia alternative in pediatric radiotherapy: A Multi-Center Pilot

3 years - 10 years
All genders
Interventional
The purpose of this study is to reduce the use of anesthesia during radiation treatments for children.
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A Phase III International Randomized Controlled Study of Rigosertib Versus Physician's Choice of Treatment in Patients With Myelodysplastic Syndrome After Failure of a Hypomethylating Agent

18 years - 81 years
All genders
The study's primary objective [in a population of patients with MDS after failure of treatment with azacitidine (AZA) or decitabine (DAC)], is to compare the overall survival (OS) of patients in the rigosertib group vs the Physician's Choice group, in all patients and in a subgroup of patients with IPSS-R …
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A RANDOMIZED, PHASE II STUDY COMPARING TRASTUZUMAB AND VINORELBINE IN COMBINATION WITH AVELUMAB OR AVELUMAB AND UTOMILUMAB (41BB/CD137 AGONIST), IN PATIENTS WITH HER2-POSITIVE METASTATIC BREAST CANCER WHO HAVE PROGRESSED ON PRIOR TRASTUZUMAB AND PERTUZUMAB:The

18 years - 100 years
All genders
Phase 2
To determine whether the addition of avelumab to the combination of trastuzumab and vinorelbine will improve progression-free survival (PFS) compared to the trastuzumab and vinorelbine combination alone in patients with advanced HER2-positive breast cancer. To determine whether the addition of utomilumab to the combination of avelumab, trastuzumab, and vinorelbine will …
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Active Music Engagement to Manage Acute Distress and Improve Positive Health Outcomes in Young Children undergoing HSCT and Parents

3 years - 8 years
All genders
We are trying to find out if music play activities can be used to help decrease parent and young child distress and improve quality of life during stem cell transplant for cancer. We also want to know if this program can help parents and young children cope better with treatment.
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A Phase III Multicenter Open Label Randomized Controlled Trial of Cefoxitin versus Piperacillin-Tazobactam as Surgical Antibiotic Prophylaxis in Patients Undergoing Pancreatoduodenectomy

18 years - 100 years
All genders
The purpose of this study is to figure out which commonly used antibiotic, cefoxitin or piperacillin-tazobactam, is better at decreasing the rate of surgical site infections after pancreatoduodenectomy.
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Assessing Exercise Behavior and Preferences Among Patients and Oncologists

Study of Exercise Habits and Support Needs in Adults With Curable Solid Tumors

18 years - 90 years
Female
The purpose of this research study is to learn about exercise habits, preferences, and barriers to exercise among adults with a current or past diagnosis of a curable solid tumor who receive care at the Indiana University Simon Cancer Center in Indianapolis, Indiana. The study will also ask cancer doctors …
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Predicting Progression of Developing Myeloma in a High Risk-Screened Population (PROMISE)

40 years - 75 years
All genders
We will further study people who test positive for these early warning signs of multiple myeloma so that we can learn how to prevent them from developing into cancer.    Your participation may help researchers find new ways to prevent and treat blood cancer.  
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A Phase 1a/1b Study of an Anti-IDO-1 Agent (LY3381916) Administered Alone or in Combination with Anti-PD-L1 Checkpoint Antibody (LY3300054) in Solid Tumors

18 years - 100 years
All genders
The purpose of this study is to evaluate the safety of the study drug LY3381916 administered alone or in combination with anti-programmed cell death ligand 1 (PD-L1) checkpoint antibody (LY3300054).
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IUCRO-0042; Blood Drawing for Study of Peripheral Blood T-Lymphocytes and Other Parameters in patients with Metastatic Melanoma and Renal Cell Cancer with Spontaneous Regression

18 years - 100 years
All genders
The purpose of this trial is to collect peripheral blood from patients with metastatic melanoma and renal cell cancer who have experienced spontaneous regression in order to study immune response.
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DEcisions about Cancer screening in Alzheimer's Disease (DECAD)

18 years - 100 years
All genders
The purpose of this study is to gain an understanding about the use of educational pamphlets by caregivers of women with dementia. This study will randomly assign caregivers to receive one of two different educational pamphlets and is designed to gather information on how caregivers make health care decisions for …
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