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Found 206 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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A Phase 2 Study of Veliparib (ABT-888) and Local Irradiation, Followed by Maintenance Veliparib and Temozolomide, in Patients With Newly Diagnosed High-Grade Glioma (HGG) Without H3 K27M or BRAFV600E Mutations

3 years - 25 years
All genders
This phase II trial studies how well veliparib, radiation therapy, and temozolomide work in treating participants with newly diagnosed malignant glioma without H3 K27M or BRAFV600E mutations.
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Genotype-directed Phase II Study of Irinotecan Dosing in Metastatic Colorectal Cancer (mCRC) Patients Receiving FOLFIRI + Bevacizumab

18 years - 100 years
All genders
This study involves standard combination chemotherapy treatment for colon cancer, 5-Fluorouracil (5FU), leucovorin and irinotecan (known as FOLFIRI), plus bevacizumab (Avastin). The study is designed to test the FOLFIRI regimen based on certain characteristics of a person's genetic makeup or "genes". Genes are made of DNA and determine not only …
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A Pilot Study Evaluating a Novel Biodynamic Imaging (BDI) Method in Predicating Response to Chemotherapy in Locoregional Esophageal Cancer

18 years - 100 years
All genders
Researchers would like to determine if a new imaging technique called Biodynamic Imagining (BDI) is appropriate for clinical use in the treatment of esophageal cancer. The purpose of this study is to determine if the tumor tissue can be collected, transported and successfully processed using BDI technology.
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The Incidence of Adjacent Synchronous Ipsilateral Infiltrating Carcinoma and/or DCIS in Patients Diagnosed with Intraductal Papilloma without Atypia or Flat Epithelial Atypia by Core Needle Biopsy

18 years - 100 years
Female
The purpose of this study is to find out how often cancer is identified by excisional biopsy near an initial core biopsy where FEA or IPWA has previously been seen.
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COLLECTION OF SPECIMENS AND CLINICAL DATA TO CREATE A BIOREPOSITORY AND REGISTRY FOR INFLAMMATORY BREAST CANCER

18 years - 100 years
All genders
The purpose of this study is to collect inflammatory breast cancer specimens. Researchers will look at differences between specimens. They will study the disease development with the goal of improving ways to prevent, diagnose and treat inflammatory breast cancer.
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A Phase II trial of Atezolizumab (anti-PDL1) with Carboplatin in Patients with Metastatic Triple Negative Breast Cancer

18 years - 100 years
All genders
The purpose of this study is to test how well the combination of study drugs, carboplatin and atezolizumab, keeps metastatic triple negative breast cancer from growing compared to taking carboplatin only.
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Cysview Blue Light Cystoscopy Registry

18 years - 100 years
All genders
The purpose of this registry is to study the use of BLCC in clinical practice in the United States and to allow researchers access to this data to look at different clinical questions.
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Key Adverse Events Following Childhood Cancer

21 years or below
All genders
The goal of this study is to identify subjects who are more likely to develop a late-occurring complication(s) after undergoing treatment for childhood cancer.
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Mechanisms of Active Music Engagement to Improve Health Outcomes of Children With Cancer and Parents

3 years - 8 years
All genders
This study investigates behavioral, social, and psychological factors that may explain how an Active Music Engagement (AME) intervention (i.e., an interactive, music-based play intervention) works to manage emotional distress and improve positive health outcomes in parents and young children with cancer during treatment.
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A Randomized Phase II Study of Pembrolizumab an anti-PD (programmed cell death)-1 Antibody in Combination with Carboplatin Compared to Carboplatin Alone in Breast Cancer Patients with Chest Wall Disease

18 years - 100 years
All genders
This study is being done to see what effects the combination of pembrolizumab and carboplatin have on breast cancer compared to carboplatin alone.
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