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Found 219 cancer trials

A listing of cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Pediatric Hepatic Malignancy International Therapeutic Trial (PHITT)

30 years or below
All genders
This trial studies how well cisplatin and combination chemotherapy works in treating children and young adults with hepatoblastoma or liver cancer after surgery.
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RNA Disruption Assay (RDA)-Breast Cancer Response Evaluation for Individualized Therapy (BREVITY / BREVITY-02 in Germany) (BREVITY)

18 years or above
Female
Interventional
The current study aims to provide validation results of RNA Disruption Assay (RDA) as a tumour response assessment tool that uses tumour core biopsies taken starting from 35 +/- 4 days after the initiation of neoadjuvant chemotherapy.
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A Randomized Phase III Trial to Evaluate the Efficacy and Safety of MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer With ? 1 CM Residual Invasive Cancer or Positive Lymph Nodes (ypN+) After Neoadjuvant Chemotherapy

18 years - 100 years
All genders
This randomized phase III trial studies how well pembrolizumab works in treating patients with triple-negative breast cancer.
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A Randomized Phase 3 Study of Vincristine Dactinomycin Cyclophosphamide (VAC) Alternating with Vincristine and Irinotecan (VI) Versus VAC/VI Plus Temsirolimus (TORI Torisel NSC# 683864 IND# 122782) in Patients with Intermediate Risk (IR) Rhabdomyosarcoma (RMS)

40 years or below
All genders
The purpose of this study is to compare the event-free survival of patients with IR RMS treated with surgery, radiotherapy and VAC alternating with VI (VAC/VI) to that of patients treated with surgery, radiotherapy and VAC/VI plus temsirolimus (TORI).
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A Randomized Phase II Study Comparing Single-Agent Olaparib, Single Agent Cediranib, and the Combination of Cediranib/Olaparib in Women With Recurrent, Persistent or Metastatic Endometrial Cancer

18 years - 100 years
Female
This phase II trial studies how well olaparib and cediranib maleate work in treating patients with endometrial cancer that has come back, does not respond to treatment, or has spread to other places in the body.
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Pilot study of the effect of weight loss on breast tissue and blood biomarkers in women at increased risk for breast cancer

18 years - 75 years
Female
The purpose of this study is to see the effects that weight loss after bariatric surgery might have on certain breast cancer biomarkers and breast density.
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Phase II Randomized Double-Blind Study of mFOLFIRINOX plus Ramucirumab versus mFOLFIRINOX plus placebo in Advanced Pancreatic Cancer Patients HCRN GI14-198

Y
Yu Wang
18 years - 100 years
All genders
The purpose of this study is to find out what effects, good and/or bad, there are to adding the drug ramucirumab (RAM) to the usual chemotherapy regimen.
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IUCRO-0209; The Susan G. Komen for a Cure Tissue Bank at IU Simon Cancer Center Collection and Storage of Biological Specimens Intended for Use in the Elucidation of Breast Carcinogenesis

18 years - 100 years
Female
The purpose of this study is to obtain and store specimens (tissue, blood, urine, or saliva) from subjects without diagnosed breast cancer compared to subjects with breast cancer.
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Feasibility, Acceptability and Preliminary Effects of the Spiritual Care Assessment and Intervention (SCAI) Framework for Adults With Advanced Cancer and Their Caregivers (FCGs): A Clinical Pilot Trial

18 years - 100 years
Accepts healthy volunteer
All genders
The purpose of this study is to test a spiritual care intervention for adults with advanced cancer and their caregivers.
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Pilot Study to Examine Correlation of Nab-Paclitaxel/Gemcitabine Pharmacokinetics with Cachexia

18 years - 100 years
All genders
The purpose of this study is to examine the relationship between body composition (i.e. muscle and fat mass) and the side effects of treatment with a commonly used chemotherapy regimen, specifically nab-paclitaxel and gemcitabine, in patients with advanced, metastatic or recurrent pancreatic cancer.
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