Comparing Observation vs Radiation for Newly Diagnosed Grade II Meningiomas that have been Completely Removed through Surgery

Recruiting
18 years - 100 years
All
Phase 3
15 participants needed
1 Location

Brief description of study

The purpose of this study is to compare the approach of observation with that of treating with radiation following surgery of a grade II meningioma.

Detailed description of study

Participants will be randomly assigned following surgery to either receive observation or to receive radiation therapy. Participants who receive radiation will do so 5 days per week for 6 1/2 to 7 weeks (33 treatments).

The doctor will continue to monitor the condition of all participants through office visits at months 3, 6 and 12 for the first year from randomization, every 6 months for year 2 and 3, then yearly for 10 years. Participants in both groups will also have MRIs at least every 6 months from randomization for 5 years, then at least yearly for 10 years.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Grade II Meningioma
  • Age: 18 years - 100 years
  • Gender: All

Individuals at least 18 years of age with a newly diagnosed grade II meningioma that has been completely removed through surgery.

Individuals with prior invasive malignancy or evidence of metastatic meningioma will not be eligible.

Individuals with certain major medical illnesses will not be eligible.

Updated on 04 Aug 2024. Study ID: 1810162883

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