Zoster Eye Disease Study (ZEDS): A multicenter, randomized trial of valacyclovir in patients with Herpes Zoster Ophthalmicus (HZO)

Primary Investigator
M

Michele Marie Spriggs

Primary Investigator

Recruiting
18 years - 100 years
All
Phase N/A
1 Location

Brief description of study

To evaluate whether or not prolonged suppressive oral antiviral treatment with valacyclovir reduces complications of HZO including new or worsening dendriform epithelial keratitis, stromal keratitis, endothelial keratitis, and/or iritis and/or postherpetic neuralgia compared to placebo.

Detailed description of study

Study location can be either the Glick Eye Institute on the IUPUI campus, or at the Glick Eye Institute Springmill, which is located on N. Illinois St.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: eye,eyes,vision,herpes zoster ophthalmicus,HZO,dendriform epithelial keratitis,stromal keratitis,endothelial keratitis,iritis,postherpetic neuralgia
  • Age: 18 years - 100 years
  • Gender: All

Eligibility Criteria
Diagnosis of HZO in one eye
 
Exclusion Criteria
Diagnosis of Leukemia, Lymphoma
Treatment with chemotherapy within the last 3 months
 

Updated on 04 Aug 2024. Study ID: 1903188647

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