Role of Aging in GCN2-dependent wound healing

Recruiting
20 years - 100 years
All
Phase N/A
1 Location

Brief description of study

Participants will be asked to provide biological samples at different time points during your pregnancy and delivery of your baby. 
 
These samples may be collected when you are getting other clinical tests done or you may be asked to have your blood drawn utilizing a drive up location or research visit. 
 
Your health information will also be collected.
When a normal healthy adult’s skin is wounded, their skin usually heals without difficulty; however, if a person damages their skin while they are sick or if they have a chronic disease, the wound may not heal as quickly. Also, as we age, the wound healing process is slowed and delayed. The purpose of this study is to examine acute wound healing to determine whether a specific mechanism in how we respond to stress plays a role in the aging-related decline in wound healing. It will determine whether defects in this stress response occur with age and if it suppresses wound healing.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Healthy
  • Age: 20 years - 100 years
  • Gender: All

Participants will be asked to provide biological samples at different time points during your pregnancy and delivery of your baby. 
 
These samples may be collected when you are getting other clinical tests done or you may be asked to have your blood drawn utilizing a drive up location or research 4 visit. 
 
Your health information will also be collected.
Inclusion Criteria
1.Age: either between 20-28 years old or at least 65 years old
2.Good general health
Exclusion Criteria
1.Diagnosis of diabetes mellitus
2.History of abnormal scarring
3.History of immunosuppression
4.History of abnormal skin infections
5.Allergies to xylocaine anesthetic
6.History of bleeding disorders
7.Use of anticoagulants
8.Unable to understand informed consent document

Updated on 04 Aug 2024. Study ID: 1909990266

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